Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MIS12Putative minichromosome instability protein. (242 aa)    
Predicted Functional Partners:
A0A251TPJ2
Putative histone-fold, Kinetochore component CENP-S.
      
 0.586
A0A251RL08
SKA2 domain-containing protein.
     
  0.540
A0A251TIJ0
Uncharacterized protein.
     
  0.540
A0A251UUS8
Putative Kinetochore-Ndc80 complex, subunit Spc25.
     
  0.540
A0A251VAC1
Uncharacterized protein.
     
  0.540
A0A251V6N2
Putative kinetochore protein Ndc80.
     
 0.505
A0A251V7I5
Putative kinetochore protein Ndc80.
     
 0.505
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.