STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECR1Putive biquitin-activating enzyme, E1, active site protein. (449 aa)    
Predicted Functional Partners:
AXR1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
   
 0.998
A0A251RXX7
Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.973
A0A251SHK1
Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.973
A0A251U016
Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.973
A0A251VDZ4
Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.973
A0A251URZ4
Putative NAD(P)-binding Rossmann-fold superfamily protein.
     
0.870
A0A251TC62
Putative SKP1/BTB/POZ domain-containing protein.
   
 
 0.868
A0A251T1Z3
Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
  
 0.866
A0A251T5D9
Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
  
 0.866
UBC13
Putative ubiquitin-conjugating enzyme 13; Belongs to the ubiquitin-conjugating enzyme family.
  
 0.866
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.