STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMDH2-23-hydroxy-3-methylglutaryl coenzyme A reductase. (597 aa)    
Predicted Functional Partners:
MVA1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.997
MVK
Mevalonate kinase.
  
 0.988
HMCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.974
CYP51G1
Putative CYTOCHROME P450 51G1; Belongs to the cytochrome P450 family.
   
  
 0.770
A0A251TL79
Putative ubiA prenyltransferase family, 2-carboxy-1,4-naphthoquinone phytyltransferase.
   
 
 0.740
A0A251TVF4
Putative transposase, Ptta/En/Spm, plant.
   
 
 0.740
FPPS
Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.723
GPPS
Putative geranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
  
 
 0.696
ISPE
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic.
     
 0.680
A0A251TBE0
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Belongs to the diphosphomevalonate decarboxylase family.
  
  
 0.673
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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