close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A251SVM0Protein kinase domain-containing protein. (939 aa)    
Predicted Functional Partners:
MCM31
DNA helicase.
   
 0.995
ATRAD3
Putative ataxia telangiectasia-mutated and RAD3-related protein; Belongs to the PI3/PI4-kinase family.
    
 0.993
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.988
MCM4-2
DNA helicase; Belongs to the MCM family.
   
 0.988
MCM8
Putative DNA helicase MCM8; Belongs to the MCM family.
   
 0.984
MCM6
DNA helicase; Belongs to the MCM family.
   
 0.984
A0A251S9D4
Uncharacterized protein.
   
 0.982
MCM10
Putative minichromosome maintenance 10.
   
 0.982
A0A251RXW4
Putative P-loop containing nucleoside triphosphate hydrolase.
   
 0.981
A0A251ST95
Putative P-loop containing nucleoside triphosphate hydrolase.
   
 0.981
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.