A0A251T0R8 protein (Helianthus annuus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

A0A251T0R8

Putative NAD(P)-binding domain-containing protein. (161 aa)

Predicted Functional Partners:

A0A251SS10

0.740

A0A251VRJ8

0.740

ARA1

0.584

A0A251SG39

0.584

A0A251T6B6

0.584

A0A251TKA5

0.584

A0A251TLB7

0.584

A0A251UL20

0.584

GAL1

0.584

GalAK

0.584

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251SG39	A0A251SS10	A0A251SG39	A0A251SS10	Uncharacterized protein.	Putative thylakoid lumenal P17.1 protein.	0.938
A0A251SG39	A0A251T0R8	A0A251SG39	A0A251T0R8	Uncharacterized protein.	Putative NAD(P)-binding domain-containing protein.	0.584
A0A251SG39	A0A251VRJ8	A0A251SG39	A0A251VRJ8	Uncharacterized protein.	Putative UTP:galactose-1-phosphate uridylyltransferase,ribose-5-phosphate adenylyltransferase.	0.938
A0A251SS10	A0A251SG39	A0A251SS10	A0A251SG39	Putative thylakoid lumenal P17.1 protein.	Uncharacterized protein.	0.938
A0A251SS10	A0A251T0R8	A0A251SS10	A0A251T0R8	Putative thylakoid lumenal P17.1 protein.	Putative NAD(P)-binding domain-containing protein.	0.740
A0A251SS10	A0A251T6B6	A0A251SS10	A0A251T6B6	Putative thylakoid lumenal P17.1 protein.	Uncharacterized protein.	0.938
A0A251SS10	A0A251TKA5	A0A251SS10	A0A251TKA5	Putative thylakoid lumenal P17.1 protein.	Putative remorin.	0.938
A0A251SS10	A0A251TLB7	A0A251SS10	A0A251TLB7	Putative thylakoid lumenal P17.1 protein.	Putative remorin.	0.938
A0A251SS10	A0A251UL20	A0A251SS10	A0A251UL20	Putative thylakoid lumenal P17.1 protein.	Putative remorin.	0.938
A0A251SS10	ARA1	A0A251SS10	A0A251RLN7	Putative thylakoid lumenal P17.1 protein.	Putative arabinose kinase.	0.938
A0A251SS10	GAL1	A0A251SS10	A0A251UPN3	Putative thylakoid lumenal P17.1 protein.	Putative mevalonate/galactokinase family protein.	0.938
A0A251SS10	GalAK	A0A251SS10	A0A251V7U7	Putative thylakoid lumenal P17.1 protein.	Putative galacturonic acid kinase.	0.938
A0A251T0R8	A0A251SG39	A0A251T0R8	A0A251SG39	Putative NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.584
A0A251T0R8	A0A251SS10	A0A251T0R8	A0A251SS10	Putative NAD(P)-binding domain-containing protein.	Putative thylakoid lumenal P17.1 protein.	0.740
A0A251T0R8	A0A251T6B6	A0A251T0R8	A0A251T6B6	Putative NAD(P)-binding domain-containing protein.	Uncharacterized protein.	0.584
A0A251T0R8	A0A251TKA5	A0A251T0R8	A0A251TKA5	Putative NAD(P)-binding domain-containing protein.	Putative remorin.	0.584
A0A251T0R8	A0A251TLB7	A0A251T0R8	A0A251TLB7	Putative NAD(P)-binding domain-containing protein.	Putative remorin.	0.584
A0A251T0R8	A0A251UL20	A0A251T0R8	A0A251UL20	Putative NAD(P)-binding domain-containing protein.	Putative remorin.	0.584
A0A251T0R8	A0A251VRJ8	A0A251T0R8	A0A251VRJ8	Putative NAD(P)-binding domain-containing protein.	Putative UTP:galactose-1-phosphate uridylyltransferase,ribose-5-phosphate adenylyltransferase.	0.740
A0A251T0R8	ARA1	A0A251T0R8	A0A251RLN7	Putative NAD(P)-binding domain-containing protein.	Putative arabinose kinase.	0.584

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.903

expected number of edges:

11

PPI enrichment p-value:

3.04e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009073

Aromatic amino acid family biosynthetic process

6 of 17

2.31

4.48

6.10e-10

GO:0009423

Chorismate biosynthetic process

3 of 6

2.46

2.3

4.79e-05

GO:0008652

Cellular amino acid biosynthetic process

5 of 101

1.45

1.58

6.07e-05

GO:0009095

Aromatic amino acid family biosynthetic process, prephenate pathway

2 of 3

2.58

1.51

0.0017

GO:0019752

Carboxylic acid metabolic process

7 of 268

1.18

1.27

3.03e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016832

Aldehyde-lyase activity

3 of 6

2.46

1.95

0.00023

GO:0016829

Lyase activity

5 of 124

1.36

1.26

0.00047

GO:0003824

Catalytic activity

11 of 2380

0.42

0.33

0.0051

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

4 of 254

0.96

0.53

0.0373

GO:0005737

Cytoplasm

8 of 1168

0.59

0.39

0.0213

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:22238540

(2011) Natural product biosyntheses in cyanobacteria: A treasure trove of unique enzymes.

2 of 4

2.46

0.86

0.0272

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1191

Phenylalanine, tyrosine and tryptophan biosynthesis

6 of 21

2.21

4.26

1.00e-09

CL:953

Biosynthesis of amino acids, and Carbon metabolism

11 of 179

1.55

3.37

1.78e-14

CL:960

Pentose phosphate pathway, and Glycolytic process

5 of 23

2.1

3.21

1.64e-07

CL:1192

Aromatic amino acid biosynthesis, and Glycosyl transferase, family 3

4 of 16

2.16

2.66

4.44e-06

CL:1211

Chorismate biosynthetic process

3 of 6

2.46

2.34

3.91e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

mar00400

Phenylalanine, tyrosine and tryptophan biosynthesis

6 of 19

2.26

4.88

4.18e-11

mar00710

Carbon fixation in photosynthetic organisms

5 of 19

2.18

3.92

5.06e-09

mar00030

Pentose phosphate pathway

5 of 19

2.18

3.92

5.06e-09

mar01230

Biosynthesis of amino acids

9 of 104

1.7

3.75

7.93e-13

mar01110

Biosynthesis of secondary metabolites

10 of 301

1.28

2.08

4.18e-11

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

8 of 1001

0.66

0.45

0.0120

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0057

Aromatic amino acid biosynthesis

4 of 14

2.21

2.76

3.31e-06

KW-0456

Lyase

4 of 87

1.42

1.23

0.00090

KW-0786

Thiamine pyrophosphate

2 of 10

2.06

1.06

0.0099

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF09364

XFP N-terminal domain

2 of 3

2.58

0.97

0.0172

PF02780

Transketolase, C-terminal domain

2 of 5

2.36

0.95

0.0180

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029061

Thiamin diphosphate-binding fold

4 of 14

2.21

2.37

2.30e-05

IPR009014

Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II

3 of 8

2.33

1.76

0.00049

IPR005474

Transketolase, N-terminal

2 of 4

2.46

0.92

0.0210

IPR033248

Transketolase, C-terminal domain

2 of 5

2.36

0.9

0.0220

IPR005475

Transketolase-like, pyrimidine-binding domain

2 of 6

2.28

0.88

0.0235

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00861

Transketolase, pyrimidine binding domain

2 of 4

2.46

1.24

0.0053

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