A0A251TEY5 protein (Helianthus annuus) - STRING interaction network

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Predicted Interactions

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A0A251TEY5

Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1021 aa)

Predicted Functional Partners:

A0A251TIJ0

0.750

PPK1

0.698

A0A251V1J1

0.698

BUBR1

0.697

A0A251SLF1

0.697

A0A251TG90

0.697

ZWI

0.692

ATRAD3

0.673

A0A251V6N2

0.671

A0A251V7I5

0.671

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251SLF1	A0A251TEY5	A0A251SLF1	A0A251TEY5	Putative mad3/BUB1 homology region 1.	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.697
A0A251SLF1	A0A251TIJ0	A0A251SLF1	A0A251TIJ0	Putative mad3/BUB1 homology region 1.	Uncharacterized protein.	0.982
A0A251SLF1	A0A251V1J1	A0A251SLF1	A0A251V1J1	Putative mad3/BUB1 homology region 1.	Protein kinase domain-containing protein.	0.920
A0A251SLF1	A0A251V6N2	A0A251SLF1	A0A251V6N2	Putative mad3/BUB1 homology region 1.	Putative kinetochore protein Ndc80.	0.974
A0A251SLF1	A0A251V7I5	A0A251SLF1	A0A251V7I5	Putative mad3/BUB1 homology region 1.	Putative kinetochore protein Ndc80.	0.974
A0A251SLF1	PPK1	A0A251SLF1	A0A251UQU6	Putative mad3/BUB1 homology region 1.	Protein kinase domain-containing protein.	0.920
A0A251SLF1	ZWI	A0A251SLF1	A0A251SI11	Putative mad3/BUB1 homology region 1.	Putative kinesin-like calmodulin-binding protein (ZWICHEL); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.401
A0A251TEY5	A0A251SLF1	A0A251TEY5	A0A251SLF1	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative mad3/BUB1 homology region 1.	0.697
A0A251TEY5	A0A251TG90	A0A251TEY5	A0A251TG90	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative ATP binding,protein serine/threonine kinase.	0.697
A0A251TEY5	A0A251TIJ0	A0A251TEY5	A0A251TIJ0	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.750
A0A251TEY5	A0A251V1J1	A0A251TEY5	A0A251V1J1	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein kinase domain-containing protein.	0.698
A0A251TEY5	A0A251V6N2	A0A251TEY5	A0A251V6N2	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative kinetochore protein Ndc80.	0.671
A0A251TEY5	A0A251V7I5	A0A251TEY5	A0A251V7I5	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative kinetochore protein Ndc80.	0.671
A0A251TEY5	ATRAD3	A0A251TEY5	A0A251UPB5	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative ataxia telangiectasia-mutated and RAD3-related protein; Belongs to the PI3/PI4-kinase family.	0.673
A0A251TEY5	BUBR1	A0A251TEY5	A0A251SDX4	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative BUB1-related (BUB1: budding uninhibited by benzymidazol 1).	0.697
A0A251TEY5	PPK1	A0A251TEY5	A0A251UQU6	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein kinase domain-containing protein.	0.698
A0A251TEY5	ZWI	A0A251TEY5	A0A251SI11	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Putative kinesin-like calmodulin-binding protein (ZWICHEL); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.692
A0A251TG90	A0A251TEY5	A0A251TG90	A0A251TEY5	Putative ATP binding,protein serine/threonine kinase.	Putative kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.697
A0A251TG90	A0A251TIJ0	A0A251TG90	A0A251TIJ0	Putative ATP binding,protein serine/threonine kinase.	Uncharacterized protein.	0.982
A0A251TG90	A0A251V1J1	A0A251TG90	A0A251V1J1	Putative ATP binding,protein serine/threonine kinase.	Protein kinase domain-containing protein.	0.920

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

31

PPI enrichment p-value:

2.05e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006123

Mitochondrial electron transport, cytochrome c to oxygen

2 of 8

2.93

1.67

0.0033

GO:0032465

Regulation of cytokinesis

2 of 12

2.75

1.52

0.0054

GO:0006122

Mitochondrial electron transport, ubiquinol to cytochrome c

2 of 12

2.75

1.52

0.0054

GO:0007052

Mitotic spindle organization

2 of 25

2.43

1.21

0.0148

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035175

Histone kinase activity (H3-S10 specific)

2 of 2

3.53

2.09

0.00083

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032133

Chromosome passenger complex

2 of 2

3.53

2.35

0.00035

GO:0051233

Spindle midzone

2 of 5

3.13

2.17

0.00061

GO:0005758

Mitochondrial intermembrane space

2 of 24

2.45

1.45

0.0063

GO:0005876

Spindle microtubule

2 of 32

2.33

1.4

0.0072

GO:0070469

Respirasome

2 of 89

1.88

0.92

0.0338

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37175542

(2023) Apostasia Mitochondrial Genome Analysis and Monocot Mitochondria Phylogenomics.

2 of 2

3.53

2.79

7.81e-05

PMID:36463111

(2022) Comparative analysis of mitochondrial genomes reveals marine adaptation in seagrasses.

2 of 2

3.53

2.79

7.81e-05

PMID:31547213

(2019) Comparison of Whole Plastome Sequences between Thermogenic Skunk Cabbage Symplocarpus renifolius and Nonthermogenic S. nipponicus (Orontioideae; Araceae) in East Asia.

2 of 2

3.53

2.79

7.81e-05

PMID:24428220

(2014) Halorhabdus tiamatea: proteogenomics and glycosidase activity measurements identify the first cultivated euryarchaeon from a deep-sea anoxic brine lake as potential polysaccharide degrader.

2 of 2

3.53

2.79

7.81e-05

PMID:23637852

(2013) The complete sequence of the mitochondrial genome of Butomus umbellatus--a member of an early branching lineage of monocotyledons.

2 of 2

3.53

2.79

7.81e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7007

Aurora kinase-like, and PIR2-like, helical domain

2 of 6

3.05

1.45

0.0072

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map05132

Salmonella infection

2 of 36

2.28

1.38

0.0075

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-111471

Apoptotic factor-mediated response

2 of 2

3.53

2.35

0.00035

MAP-111457

Release of apoptotic factors from the mitochondria

2 of 2

3.53

2.35

0.00035

MAP-5620971

Pyroptosis

2 of 3

3.35

2.34

0.00035

MAP-5218859

Regulated Necrosis

2 of 7

2.99

2.26

0.00043

MAP-109606

Intrinsic Pathway for Apoptosis

2 of 23

2.47

1.71

0.0025

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032133

Chromosome passenger complex

2 of 5

3.13

1.86

0.0018

GOCC:0051233

Spindle midzone

2 of 7

2.99

1.85

0.0018

GOCC:0005758

Mitochondrial intermembrane space

2 of 34

2.3

1.14

0.0184

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0679

Respiratory chain

2 of 16

2.63

1.66

0.0032

KW-0496

Mitochondrion

2 of 75

1.96

1.07

0.0200

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00034

Cytochrome c

2 of 2

3.53

2.11

0.00079

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030616

Aurora kinase-like

2 of 2

3.53

1.79

0.0023

IPR002327

Cytochrome c, class IA/ IB

2 of 2

3.53

1.79

0.0023

IPR036909

Cytochrome c-like domain superfamily

2 of 6

3.05

1.65

0.0036

IPR009056

Cytochrome c-like domain

2 of 7

2.99

1.65

0.0036

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