STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCNA2Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (364 aa)    
Predicted Functional Partners:
AtLIG6
DNA ligase.
  
 0.985
RFC2-2
Putative replication factor C.
  
 0.984
DPOD1
DNA polymerase.
  
 0.978
POLD2
Putative DNA polymerase delta small subunit.
   
 0.976
RFC3
Putative replication factor C subunit 3.
  
 0.975
REV1
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
   
 0.971
RFC1
Replication factor C subunit 1.
   
 0.963
A0A251TML7
Putative P-loop containing nucleoside triphosphate hydrolases superfamily protein.
   
 0.963
DPOLA
DNA polymerase.
  
 0.960
A0A251SGB6
Putative umuC domain-containing protein.
   
 0.958
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.