STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coxICytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (564 aa)    
Predicted Functional Partners:
coxIII
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.
 
 0.996
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
 
 0.994
A0A251SPL0
Uncharacterized protein.
  
 0.986
A0A1Y3BUN2
Putative cupredoxin.
 
 0.976
A0A251UZZ0
Putative cupredoxin, Cytochrome C oxidase subunit II, transmembrane domain protein.
 
 0.971
nad1
NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family.
   
 0.960
A0A251S128
Putative cytochrome c oxidase, subunit Vb.
   
 0.958
A0A251TLF1
Putative rubredoxin-like superfamily protein.
   
 0.958
A0A251RMI4
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.950
A0A251RQB4
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.950
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.