STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (348 aa)    
Predicted Functional Partners:
SJZ59586.1
CDP-diacylglycerol---serine O-phosphatidyltransferase.
 
  
 0.855
SJZ59594.1
Phosphate starvation-inducible protein PhoH.
       0.594
ybeY
Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.594
SJZ59611.1
Protein of unknown function.
       0.594
SJZ59658.1
Hypothetical protein.
       0.586
SJZ58593.1
Tetratricopeptide repeat-containing protein.
 
 
 0.585
SJZ59638.1
Hypothetical protein.
       0.582
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.582
SJZ78499.1
ABC-2 type transport system permease protein.
    
  0.539
SJZ99803.1
Lipid kinase, YegS/Rv2252/BmrU family.
  
 
  0.537
Your Current Organism:
Eubacterium ruminantium
NCBI taxonomy Id: 42322
Other names: ATCC 17233, DSM 20704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.