node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ50597.1 | SJZ66430.1 | SAMN02745110_00709 | SAMN02745110_01228 | Peroxiredoxin family protein. | Phosphoribosylformylglycinamidine synthase. | 0.442 |
SJZ50597.1 | SJZ75420.1 | SAMN02745110_00709 | SAMN02745110_01521 | Peroxiredoxin family protein. | Ribose-5-phosphate isomerase. | 0.679 |
SJZ50597.1 | SJZ76857.1 | SAMN02745110_00709 | SAMN02745110_01527 | Peroxiredoxin family protein. | Amino acid adenylation domain-containing protein. | 0.999 |
SJZ50597.1 | SJZ83009.1 | SAMN02745110_00709 | SAMN02745110_01712 | Peroxiredoxin family protein. | Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family. | 0.658 |
SJZ50597.1 | fhs | SAMN02745110_00709 | SAMN02745110_00981 | Peroxiredoxin family protein. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.441 |
SJZ50597.1 | folD | SAMN02745110_00709 | SAMN02745110_00982 | Peroxiredoxin family protein. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.624 |
SJZ50597.1 | glyA | SAMN02745110_00709 | SAMN02745110_01533 | Peroxiredoxin family protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.934 |
SJZ66430.1 | SJZ50597.1 | SAMN02745110_01228 | SAMN02745110_00709 | Phosphoribosylformylglycinamidine synthase. | Peroxiredoxin family protein. | 0.442 |
SJZ66430.1 | SJZ75420.1 | SAMN02745110_01228 | SAMN02745110_01521 | Phosphoribosylformylglycinamidine synthase. | Ribose-5-phosphate isomerase. | 0.425 |
SJZ66430.1 | SJZ76857.1 | SAMN02745110_01228 | SAMN02745110_01527 | Phosphoribosylformylglycinamidine synthase. | Amino acid adenylation domain-containing protein. | 0.591 |
SJZ66430.1 | SJZ81017.1 | SAMN02745110_01228 | SAMN02745110_01664 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.999 |
SJZ66430.1 | fhs | SAMN02745110_01228 | SAMN02745110_00981 | Phosphoribosylformylglycinamidine synthase. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.942 |
SJZ66430.1 | folD | SAMN02745110_01228 | SAMN02745110_00982 | Phosphoribosylformylglycinamidine synthase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.862 |
SJZ66430.1 | glyA | SAMN02745110_01228 | SAMN02745110_01533 | Phosphoribosylformylglycinamidine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.974 |
SJZ66430.1 | purN | SAMN02745110_01228 | SAMN02745110_01709 | Phosphoribosylformylglycinamidine synthase. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
SJZ75420.1 | SJZ50597.1 | SAMN02745110_01521 | SAMN02745110_00709 | Ribose-5-phosphate isomerase. | Peroxiredoxin family protein. | 0.679 |
SJZ75420.1 | SJZ66430.1 | SAMN02745110_01521 | SAMN02745110_01228 | Ribose-5-phosphate isomerase. | Phosphoribosylformylglycinamidine synthase. | 0.425 |
SJZ75420.1 | SJZ76857.1 | SAMN02745110_01521 | SAMN02745110_01527 | Ribose-5-phosphate isomerase. | Amino acid adenylation domain-containing protein. | 0.829 |
SJZ75420.1 | SJZ81017.1 | SAMN02745110_01521 | SAMN02745110_01664 | Ribose-5-phosphate isomerase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.845 |
SJZ75420.1 | SJZ83009.1 | SAMN02745110_01521 | SAMN02745110_01712 | Ribose-5-phosphate isomerase. | Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family. | 0.842 |