STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SJZ77472.1Signal peptidase, endoplasmic reticulum-type. (250 aa)    
Predicted Functional Partners:
SJZ77462.1
Hypothetical protein.
 
     0.758
SJZ77438.1
Protein of unknown function.
 
     0.743
SJZ89338.1
Purine-nucleoside phosphorylase.
    
 0.654
pyrD
Dihydroorotate dehydrogenase (NAD+) catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.621
SJZ77547.1
Hypothetical protein.
       0.610
SJZ53473.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.595
SJZ36691.1
Thymidine phosphorylase.
    
 0.594
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.591
SJZ40498.1
Adenosine deaminase.
   
 0.590
SJZ83315.1
4Fe-4S dicluster domain-containing protein.
  
 
 0.588
Your Current Organism:
Eubacterium ruminantium
NCBI taxonomy Id: 42322
Other names: ATCC 17233, DSM 20704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.