STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKA03999.1N-acetylglutamate synthase, GNAT family. (151 aa)    
Predicted Functional Partners:
SKA04017.1
Hypothetical protein.
       0.658
SJZ73937.1
Two-component system, NarL family, sensor histidine kinase DegS.
   
 
  0.637
SJZ58593.1
Tetratricopeptide repeat-containing protein.
  
  
 0.595
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.579
SJZ95530.1
DNA topoisomerase IV subunit B.
    
 
 0.579
SKA04038.1
L-2-amino-thiazoline-4-carboxylic acid hydrolase.
       0.513
SJZ51198.1
DUF4097 and DUF4098 domain-containing protein YvlB.
    
   0.459
SKA03977.1
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases.
       0.433
SKA03954.1
CAAX protease self-immunity.
       0.421
Your Current Organism:
Eubacterium ruminantium
NCBI taxonomy Id: 42322
Other names: ATCC 17233, DSM 20704
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.