STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEN77065.1Thiol-disulfide isomerase or thioredoxin. (226 aa)    
Predicted Functional Partners:
msrB
Peptide methionine sulfoxide reductase msrA/msrB.
   
 0.986
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.986
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.967
SEO45588.1
Dihydrolipoamide dehydrogenase.
  
 0.933
SEN95984.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit.
   
   0.891
SEO87682.1
Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin).
  
 0.865
SEP08052.1
Peroxiredoxin (alkyl hydroperoxide reductase subunit C).
  
 0.865
SEO33718.1
Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family.
   
 
 0.830
SEN93958.1
Dihydrolipoamide dehydrogenase.
   
 0.828
SEO60920.1
Dihydrolipoamide dehydrogenase.
   
 0.828
Your Current Organism:
Nitrosomonas oligotropha
NCBI taxonomy Id: 42354
Other names: N. oligotropha, Nitrosomonas oligotropha Koops et al. 2001, strain Nm 45
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