STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSAT_8X26380Lon proteolytic domain-containing protein. (245 aa)    
Predicted Functional Partners:
LSAT_5X53600
Uncharacterized protein.
    
 
 0.714
MED10
Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
 0.681
LSAT_1X58740
Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.
   
 
 0.681
LSAT_5X68981
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.555
LSAT_8X45520
Protein kinase domain-containing protein.
   
 
 0.555
LSAT_8X11541
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.552
LSAT_3X137161
Med12 domain-containing protein.
    
 
 0.511
LSAT_4X85361
Inositol polyphosphate multikinase; Inositol phosphate kinase with a broad substrate specificity.
    
 
 0.437
LSAT_1X29881
Inositol polyphosphate multikinase; Inositol phosphate kinase with a broad substrate specificity.
    
 
 0.437
LSAT_8X93980
JmjC domain-containing protein.
     
 0.431
Your Current Organism:
Lactuca sativa
NCBI taxonomy Id: 4236
Other names: L. sativa, Lactuca sativa L., cultivated lettuce, garden lettuce
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