STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSAT_8X124281HECT domain-containing protein. (1799 aa)    
Predicted Functional Partners:
LSAT_4X33481
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.994
LSAT_8X81981
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.994
LSAT_1X53840
HECT domain-containing protein.
  
  
 
0.906
LSAT_7X19080
WAPL domain-containing protein.
   
    0.890
LSAT_7X1081
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.850
LSAT_7X1281
Ubiquitin-like domain-containing protein.
   
 0.850
LSAT_1X127601
Uncharacterized protein.
   
 0.850
LSAT_7X16760
Uncharacterized protein.
   
 0.850
LSAT_8X111880
Uncharacterized protein.
   
 0.850
LSAT_5X103881
Uncharacterized protein.
   
 0.850
Your Current Organism:
Lactuca sativa
NCBI taxonomy Id: 4236
Other names: L. sativa, Lactuca sativa L., cultivated lettuce, garden lettuce
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