STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSAT_8X89101Protein kinase domain-containing protein. (431 aa)    
Predicted Functional Partners:
LSAT_1X20280
Uncharacterized protein.
    
   0.785
LSAT_9X46201
ORC_WH_C domain-containing protein.
    
   0.785
LSAT_5X120180
DNA helicase; Belongs to the MCM family.
    
   0.785
LSAT_7X4881
AAA_16 domain-containing protein.
    
   0.785
LSAT_7X30521
MCM domain-containing protein; Belongs to the MCM family.
    
   0.785
LSAT_2X97601
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
    
   0.655
LSAT_8X54000
Uncharacterized protein.
    
   0.606
LSAT_3X11020
Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
    
   0.606
LSAT_9X8740
CDT1 domain-containing protein.
    
   0.606
LSAT_9X10441
CDT1 domain-containing protein.
    
   0.606
Your Current Organism:
Lactuca sativa
NCBI taxonomy Id: 4236
Other names: L. sativa, Lactuca sativa L., cultivated lettuce, garden lettuce
Server load: low (30%) [HD]