STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ssed_1908Hydrogen:quinone oxidoreductase; KEGG: shm:Shewmr7_2155 hydrogenase (NiFe) small subunit HydA. (378 aa)    
Predicted Functional Partners:
Ssed_1906
KEGG: shw:Sputw3181_1922 Ni/Fe-hydrogenase, b-type cytochrome subunit.
 
 0.999
Ssed_1907
KEGG: slo:Shew_1764 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.998
Ssed_1905
KEGG: slo:Shew_1762 hydrogenase expression/formation protein.
 
  
 0.951
Ssed_2273
KEGG: ppr:PBPRA1988 putative pyruvate oxidoreductase.
  
  
 0.951
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.898
Ssed_1902
KEGG: shw:Sputw3181_2173 hydrogenase accessory protein HypB.
 
  
 0.895
Ssed_1903
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.892
Ssed_1900
KEGG: sbl:Sbal_1881 hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.885
Ssed_1901
KEGG: slo:Shew_1758 hydrogenase assembly chaperone HypC/HupF.
 
 
 0.881
Ssed_1899
KEGG: slo:Shew_1756 hydrogenase expression/formation protein HypE.
 
   
 0.880
Your Current Organism:
Shewanella sediminis
NCBI taxonomy Id: 425104
Other names: S. sediminis HAW-EB3, Shewanella sediminis HAW-EB3, Shewanella sediminis str. HAW-EB3, Shewanella sediminis strain HAW-EB3
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