def-2 protein (Shewanella sediminis) - STRING interaction network

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def-2

Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (163 aa)

Predicted Functional Partners:

rplT

0.826

rplU

0.822

rplI

0.812

tig

0.797

rpsP

0.788

rpsT

0.788

rpmA

0.787

rpsU

0.782

rpsJ

0.774

rplX

0.764

Your Current Organism:

Shewanella sediminis

NCBI taxonomy Id: 425104
Other names: S. sediminis HAW-EB3, Shewanella sediminis HAW-EB3, Shewanella sediminis str. HAW-EB3, Shewanella sediminis strain HAW-EB3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def-2	rplI	Ssed_2006	Ssed_0760	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L9; Binds to the 23S rRNA.	0.812
def-2	rplT	Ssed_2006	Ssed_2123	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.826
def-2	rplU	Ssed_2006	Ssed_0954	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.822
def-2	rplX	Ssed_2006	Ssed_4306	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.764
def-2	rpmA	Ssed_2006	Ssed_0955	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	KEGG: slo:Shew_0870 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.787
def-2	rpsJ	Ssed_2006	Ssed_4318	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.774
def-2	rpsP	Ssed_2006	Ssed_1159	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	KEGG: sdn:Sden_2754 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.788
def-2	rpsT	Ssed_2006	Ssed_1191	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.788
def-2	rpsU	Ssed_2006	Ssed_1075	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	KEGG: shw:Sputw3181_3057 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.	0.782
def-2	tig	Ssed_2006	Ssed_1540	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.797
rplI	def-2	Ssed_0760	Ssed_2006	Ribosomal protein L9; Binds to the 23S rRNA.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.812
rplI	rplT	Ssed_0760	Ssed_2123	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.981
rplI	rplU	Ssed_0760	Ssed_0954	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.978
rplI	rplX	Ssed_0760	Ssed_4306	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.982
rplI	rpmA	Ssed_0760	Ssed_0955	Ribosomal protein L9; Binds to the 23S rRNA.	KEGG: slo:Shew_0870 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.978
rplI	rpsJ	Ssed_0760	Ssed_4318	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.978
rplI	rpsP	Ssed_0760	Ssed_1159	Ribosomal protein L9; Binds to the 23S rRNA.	KEGG: sdn:Sden_2754 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.976
rplI	rpsT	Ssed_0760	Ssed_1191	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.910
rplI	rpsU	Ssed_0760	Ssed_1075	Ribosomal protein L9; Binds to the 23S rRNA.	KEGG: shw:Sputw3181_3057 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.	0.922
rplI	tig	Ssed_0760	Ssed_1540	Ribosomal protein L9; Binds to the 23S rRNA.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.960

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