node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ssed_0432 | Ssed_0433 | Ssed_0432 | Ssed_0433 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 0.999 |
Ssed_0432 | Ssed_2177 | Ssed_0432 | Ssed_2177 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: gur:Gura_1611 catalytic domain of components of various dehydrogenase complexes. | 0.930 |
Ssed_0432 | gcvH | Ssed_0432 | Ssed_3674 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.646 |
Ssed_0432 | gcvP | Ssed_0432 | Ssed_3673 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.734 |
Ssed_0432 | lipA | Ssed_0432 | Ssed_3492 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.609 |
Ssed_0432 | lipB | Ssed_0432 | Ssed_3491 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.706 |
Ssed_0432 | pdhA | Ssed_0432 | Ssed_2175 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
Ssed_0433 | Ssed_0432 | Ssed_0433 | Ssed_0432 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
Ssed_0433 | Ssed_2177 | Ssed_0433 | Ssed_2177 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | KEGG: gur:Gura_1611 catalytic domain of components of various dehydrogenase complexes. | 0.997 |
Ssed_0433 | Ssed_2327 | Ssed_0433 | Ssed_2327 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; KEGG: sfr:Sfri_1937 catalytic domain of components of various dehydrogenase complexes. | 0.997 |
Ssed_0433 | Ssed_2813 | Ssed_0433 | Ssed_2813 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.997 |
Ssed_0433 | gcvH | Ssed_0433 | Ssed_3674 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.980 |
Ssed_0433 | gcvP | Ssed_0433 | Ssed_3673 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.958 |
Ssed_0433 | lipA | Ssed_0433 | Ssed_3492 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.658 |
Ssed_0433 | lipB | Ssed_0433 | Ssed_3491 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.482 |
Ssed_0433 | pdhA | Ssed_0433 | Ssed_2175 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
Ssed_2177 | Ssed_0432 | Ssed_2177 | Ssed_0432 | KEGG: gur:Gura_1611 catalytic domain of components of various dehydrogenase complexes. | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.930 |
Ssed_2177 | Ssed_0433 | Ssed_2177 | Ssed_0433 | KEGG: gur:Gura_1611 catalytic domain of components of various dehydrogenase complexes. | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 0.997 |
Ssed_2177 | gcvH | Ssed_2177 | Ssed_3674 | KEGG: gur:Gura_1611 catalytic domain of components of various dehydrogenase complexes. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.557 |
Ssed_2177 | gcvP | Ssed_2177 | Ssed_3673 | KEGG: gur:Gura_1611 catalytic domain of components of various dehydrogenase complexes. | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.634 |