lyst protein (Pygocentrus nattereri) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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[Homology]

Score

lyst

Lysosomal trafficking regulator. (3752 aa)

Predicted Functional Partners:

sqstm1

0.976

map1lc3b

0.928

map1lc3a

0.928

map1lc3c

0.907

LOC108437991

0.897

LOC108413416

0.897

LOC108432344

0.876

LOC108416673

0.876

optn

0.870

rps27a

0.864

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108413416	LOC108416673	ENSPNAP00000016068	ENSPNAP00000034045	NBR1 autophagy cargo receptor a.	Microtubule-associated protein 1 light chain 3 gamma, like.	0.991
LOC108413416	LOC108432344	ENSPNAP00000016068	ENSPNAP00000031918	NBR1 autophagy cargo receptor a.	Zgc:92606.	0.991
LOC108413416	LOC108437991	ENSPNAP00000016068	ENSPNAP00000008215	NBR1 autophagy cargo receptor a.	NBR1 autophagy cargo receptor b.	0.986
LOC108413416	lyst	ENSPNAP00000016068	ENSPNAP00000001088	NBR1 autophagy cargo receptor a.	Lysosomal trafficking regulator.	0.897
LOC108413416	map1lc3a	ENSPNAP00000016068	ENSPNAP00000022872	NBR1 autophagy cargo receptor a.	Microtubule-associated protein 1 light chain 3 alpha.	0.991
LOC108413416	map1lc3b	ENSPNAP00000016068	ENSPNAP00000001764	NBR1 autophagy cargo receptor a.	Microtubule-associated protein 1 light chain 3 beta.	0.990
LOC108413416	map1lc3c	ENSPNAP00000016068	ENSPNAP00000007519	NBR1 autophagy cargo receptor a.	Microtubule-associated protein 1 light chain 3 gamma.	0.991
LOC108413416	optn	ENSPNAP00000016068	ENSPNAP00000025853	NBR1 autophagy cargo receptor a.	Optineurin.	0.953
LOC108413416	rps27a	ENSPNAP00000016068	ENSPNAP00000008071	NBR1 autophagy cargo receptor a.	Ribosomal protein S27a.	0.991
LOC108413416	sqstm1	ENSPNAP00000016068	ENSPNAP00000031921	NBR1 autophagy cargo receptor a.	Sequestosome 1.	0.997
LOC108416673	LOC108413416	ENSPNAP00000034045	ENSPNAP00000016068	Microtubule-associated protein 1 light chain 3 gamma, like.	NBR1 autophagy cargo receptor a.	0.991
LOC108416673	LOC108437991	ENSPNAP00000034045	ENSPNAP00000008215	Microtubule-associated protein 1 light chain 3 gamma, like.	NBR1 autophagy cargo receptor b.	0.989
LOC108416673	lyst	ENSPNAP00000034045	ENSPNAP00000001088	Microtubule-associated protein 1 light chain 3 gamma, like.	Lysosomal trafficking regulator.	0.876
LOC108416673	map1lc3a	ENSPNAP00000034045	ENSPNAP00000022872	Microtubule-associated protein 1 light chain 3 gamma, like.	Microtubule-associated protein 1 light chain 3 alpha.	0.860
LOC108416673	map1lc3b	ENSPNAP00000034045	ENSPNAP00000001764	Microtubule-associated protein 1 light chain 3 gamma, like.	Microtubule-associated protein 1 light chain 3 beta.	0.860
LOC108416673	map1lc3c	ENSPNAP00000034045	ENSPNAP00000007519	Microtubule-associated protein 1 light chain 3 gamma, like.	Microtubule-associated protein 1 light chain 3 gamma.	0.903
LOC108416673	optn	ENSPNAP00000034045	ENSPNAP00000025853	Microtubule-associated protein 1 light chain 3 gamma, like.	Optineurin.	0.937
LOC108416673	sqstm1	ENSPNAP00000034045	ENSPNAP00000031921	Microtubule-associated protein 1 light chain 3 gamma, like.	Sequestosome 1.	0.957
LOC108432344	LOC108413416	ENSPNAP00000031918	ENSPNAP00000016068	Zgc:92606.	NBR1 autophagy cargo receptor a.	0.991
LOC108432344	LOC108437991	ENSPNAP00000031918	ENSPNAP00000008215	Zgc:92606.	NBR1 autophagy cargo receptor b.	0.990