Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smpd2Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase). (440 aa)    
Predicted Functional Partners:
smpd4
Sphingomyelin phosphodiesterase 4.
     
 0.986
smpd1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.985
ugcg
UDP-glucose ceramide glucosyltransferase.
     
 0.979
asah2
Neutral ceramidase.
     
 0.972
nsmaf
Neutral sphingomyelinase (N-SMase) activation associated factor.
     
 0.971
smpd3
Sphingomyelin phosphodiesterase 3, neutral.
     
 0.969
gba2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.962
acer1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.962
LOC108412216
Sphingomyelin phosphodiesterase 5.
     
 0.957
degs2
Delta(4)-desaturase, sphingolipid 2.
     
 0.955
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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