Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gucy1b1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (609 aa)    
Predicted Functional Partners:
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.993
gucy1a1
Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.993
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 0.957
pde3a
Phosphodiesterase.
   
 0.935
LOC108425710
Guanylate cyclase 1, soluble, beta 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
  
 
0.932
pde3b
Phosphodiesterase.
   
 0.931
LOC108444159
cGMP-dependent protein kinase.
   
 0.931
LOC108436964
Phosphodiesterase.
   
 0.929
pde6c
Phosphodiesterase.
   
 0.929
LOC108417948
Phosphodiesterase.
   
 0.929
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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