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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsf1Heat shock transcription factor 1. (490 aa)    
Predicted Functional Partners:
hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
    
 0.847
LOC108411468
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 0.847
LOC108411456
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
    
 0.847
tsc1
TSC complex subunit 1a.
    
 0.818
trap1
TNF receptor-associated protein 1.
    
 0.818
LOC108438099
TSC complex subunit 1b.
    
 0.818
sirt1
Sirtuin 1.
    
 0.746
ywhae
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1; Belongs to the 14-3-3 family.
    
 0.703
LOC108430458
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
    
 0.703
washc1
WAS protein family homolog 1.
   
 
 0.702
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.