Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmppeTransmembrane protein with metallophosphoesterase domain. (432 aa)    
Predicted Functional Partners:
slc66a3
Solute carrier family 66 member 3.
      
 0.720
LOC108439589
Uncharacterized protein.
      
 0.720
yipf4
Protein YIPF.
      
 0.709
dolpp1
Dolichyldiphosphatase 1.
     
 0.709
tmem41a
Transmembrane protein 41ab.
     
 0.662
LOC108410768
Transmembrane protein 41aa.
     
 0.662
tsen2
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
      
 0.608
yipf3
Yip1 domain family, member 3.
      
 0.607
unc50
Unc-50 homolog (C. elegans).
      
 0.606
sfxn4
Sideroflexin 4.
      
 0.605
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
Server load: low (28%) [HD]