Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sel1lSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (798 aa)    
Predicted Functional Partners:
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.999
ube2j1
Ubiquitin-conjugating enzyme E2, J1.
   
 
 0.993
aup1
AUP1 lipid droplet regulating VLDL assembly factor.
    
 
 0.993
edem1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.993
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.990
faf2
Fas associated factor family member 2.
   
 
 0.987
os9
OS9 endoplasmic reticulum lectin.
   
 0.987
erlec1
Endoplasmic reticulum lectin 1.
   
 0.983
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
   
 0.981
amfr
Autocrine motility factor receptor a.
   
 0.981
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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