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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC108444443APH1B gamma secretase subunit. (258 aa)    
Predicted Functional Partners:
psenen
Presenilin enhancer, gamma-secretase subunit.
   
 0.994
NCSTN
Nicastrin.
   
 0.993
LOC108423477
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.987
LOC108438591
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.986
notch1
Notch receptor 1b.
    
 0.937
LOC108413122
Notch receptor 1a.
    
 0.913
LOC108429650
Notch receptor 3.
    
 0.894
LOC108439388
Notch receptor 2.
    
 0.892
LOC108427283
Zgc:114200.
  
  
 
0.882
fat3
FAT atypical cadherin 3a.
     
 0.773
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.