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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serpinf2SERPIN domain-containing protein; Belongs to the serpin family. (470 aa)    
Predicted Functional Partners:
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
 0.942
LOC108440861
Uncharacterized protein; Belongs to the peptidase S1 family.
  
 0.869
LOC108440860
Uncharacterized protein.
  
 0.869
f2
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
  
 0.782
LOC108439170
Fibrinogen alpha chain.
   
 
 0.772
plat
Plasminogen activator; Belongs to the peptidase S1 family.
   
 0.707
ENSPNAP00000022261
Uncharacterized protein.
   
 0.675
plau
Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.
   
 0.675
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
  
0.666
LOC108430775
Uncharacterized protein.
   
 
 0.641
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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