mkrn1 protein (Pygocentrus nattereri) - STRING interaction network

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Score

mkrn1

Makorin, ring finger protein, 1. (449 aa)

Predicted Functional Partners:

trip12

0.782

cpsf2

0.744

ENSPNAP00000003651

0.651

rps27a

0.651

LOC108410538

0.581

pten

0.581

LOC108411875

0.581

fech

0.573

uba5

0.560

atg7

0.560

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNAP00000003651	LOC108410538	ENSPNAP00000003651	ENSPNAP00000019700	Ubiquitin-like domain-containing protein.	Transmembrane phosphatase with tensin homology.	0.706
ENSPNAP00000003651	LOC108411875	ENSPNAP00000003651	ENSPNAP00000027848	Ubiquitin-like domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.706
ENSPNAP00000003651	atg7	ENSPNAP00000003651	ENSPNAP00000024126	Ubiquitin-like domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.795
ENSPNAP00000003651	mkrn1	ENSPNAP00000003651	ENSPNAP00000002281	Ubiquitin-like domain-containing protein.	Makorin, ring finger protein, 1.	0.651
ENSPNAP00000003651	pten	ENSPNAP00000003651	ENSPNAP00000024549	Ubiquitin-like domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.706
ENSPNAP00000003651	rps27a	ENSPNAP00000003651	ENSPNAP00000008071	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.999
ENSPNAP00000003651	trip12	ENSPNAP00000003651	ENSPNAP00000011543	Ubiquitin-like domain-containing protein.	Thyroid hormone receptor interactor 12.	0.960
ENSPNAP00000003651	uba5	ENSPNAP00000003651	ENSPNAP00000013115	Ubiquitin-like domain-containing protein.	Ubiquitin-like modifier activating enzyme 5.	0.793
LOC108410538	ENSPNAP00000003651	ENSPNAP00000019700	ENSPNAP00000003651	Transmembrane phosphatase with tensin homology.	Ubiquitin-like domain-containing protein.	0.706
LOC108410538	mkrn1	ENSPNAP00000019700	ENSPNAP00000002281	Transmembrane phosphatase with tensin homology.	Makorin, ring finger protein, 1.	0.581
LOC108410538	rps27a	ENSPNAP00000019700	ENSPNAP00000008071	Transmembrane phosphatase with tensin homology.	Ribosomal protein S27a.	0.678
LOC108411875	ENSPNAP00000003651	ENSPNAP00000027848	ENSPNAP00000003651	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin-like domain-containing protein.	0.706
LOC108411875	mkrn1	ENSPNAP00000027848	ENSPNAP00000002281	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Makorin, ring finger protein, 1.	0.581
LOC108411875	pten	ENSPNAP00000027848	ENSPNAP00000024549	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.882
LOC108411875	rps27a	ENSPNAP00000027848	ENSPNAP00000008071	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ribosomal protein S27a.	0.678
atg7	ENSPNAP00000003651	ENSPNAP00000024126	ENSPNAP00000003651	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-like domain-containing protein.	0.795
atg7	mkrn1	ENSPNAP00000024126	ENSPNAP00000002281	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Makorin, ring finger protein, 1.	0.560
atg7	rps27a	ENSPNAP00000024126	ENSPNAP00000008071	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ribosomal protein S27a.	0.786
atg7	trip12	ENSPNAP00000024126	ENSPNAP00000011543	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.987
atg7	uba5	ENSPNAP00000024126	ENSPNAP00000013115	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-like modifier activating enzyme 5.	0.814