LOC108426389 protein (Pygocentrus nattereri)

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LOC108426389

Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (116 aa)

Predicted Functional Partners:

rpa1

0.981

rpa3

0.974

fancm

0.972

wrn

0.970

rad52

0.954

atr

0.926

pcna

0.923

blm

0.918

LOC108443732

0.917

meiob

0.909

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108426389	LOC108443732	ENSPNAP00000002435	ENSPNAP00000002181	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.917
LOC108426389	atr	ENSPNAP00000002435	ENSPNAP00000013968	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.926
LOC108426389	blm	ENSPNAP00000002435	ENSPNAP00000005509	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	BLM RecQ like helicase.	0.918
LOC108426389	fancm	ENSPNAP00000002435	ENSPNAP00000028001	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein.	0.972
LOC108426389	meiob	ENSPNAP00000002435	ENSPNAP00000004083	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Methionine sulfoxide reductase B1b.	0.909
LOC108426389	pcna	ENSPNAP00000002435	ENSPNAP00000012004	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.923
LOC108426389	rad52	ENSPNAP00000002435	ENSPNAP00000012326	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	RAD52 homolog, DNA repair protein.	0.954
LOC108426389	rpa1	ENSPNAP00000002435	ENSPNAP00000002042	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.981
LOC108426389	rpa3	ENSPNAP00000002435	ENSPNAP00000035245	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Replication protein A3.	0.974
LOC108426389	wrn	ENSPNAP00000002435	ENSPNAP00000015793	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	WRN RecQ like helicase.	0.970
LOC108443732	LOC108426389	ENSPNAP00000002181	ENSPNAP00000002435	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.917
LOC108443732	blm	ENSPNAP00000002181	ENSPNAP00000005509	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	BLM RecQ like helicase.	0.539
LOC108443732	meiob	ENSPNAP00000002181	ENSPNAP00000004083	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Methionine sulfoxide reductase B1b.	0.844
LOC108443732	pcna	ENSPNAP00000002181	ENSPNAP00000012004	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
LOC108443732	rpa1	ENSPNAP00000002181	ENSPNAP00000002042	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.875
LOC108443732	rpa3	ENSPNAP00000002181	ENSPNAP00000035245	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	Replication protein A3.	0.711
LOC108443732	wrn	ENSPNAP00000002181	ENSPNAP00000015793	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	WRN RecQ like helicase.	0.615
atr	LOC108426389	ENSPNAP00000013968	ENSPNAP00000002435	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.926
atr	blm	ENSPNAP00000013968	ENSPNAP00000005509	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	BLM RecQ like helicase.	0.978
atr	fancm	ENSPNAP00000013968	ENSPNAP00000028001	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.997

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