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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pde8aPhosphodiesterase. (787 aa)    
Predicted Functional Partners:
adcy5
Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
     
 0.889
ak9
Adenylate kinase 9.
     
 0.888
enpp1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.887
LOC108429235
Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
     
 0.883
adcy9
Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
     
 0.883
adcy6
Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
     
 0.883
LOC108416099
Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
     
 0.883
ampd1
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
     
 0.881
nt5e
5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.
     
 0.880
ak2
Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
     
 0.878
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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