Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC108433748Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (429 aa)    
Predicted Functional Partners:
ENSPNAP00000016200
Glycogen synthase kinase binding protein.
    
 0.963
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
    
 0.952
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.942
LOC108414240
Catenin, beta 2.
    
 0.942
tsc2
TSC complex subunit 2.
    
 0.941
apc
APC regulator of WNT signaling pathway.
    
 0.928
apc2
APC regulator of WNT signaling pathway 2.
    
 0.928
LOC108438591
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.903
LOC108423477
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.903
axin1
Axin 1.
    
 0.900
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
Server load: medium (48%) [HD]