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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPNAP00000004243TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (274 aa)    
Predicted Functional Partners:
TNFRSF11B
TNF receptor superfamily member 11b.
    
 0.989
LOC108425552
Uncharacterized protein.
    
 0.805
LOC108443670
Uncharacterized protein.
    
 0.798
tnfrsf11a
Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.
    
 0.783
tnfsf13b
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 0.770
ENSPNAP00000009474
Uncharacterized protein.
   
 0.760
LOC108442901
TNFR-Cys domain-containing protein.
   
 0.760
LOC108414112
TNFR-Cys domain-containing protein.
   
 0.760
LOC108414118
Uncharacterized protein.
   
 0.760
LOC108414119
TNFR-Cys domain-containing protein.
   
 0.760
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.