dyrk3 protein (Pygocentrus nattereri) - STRING interaction network

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Score

dyrk3

Dual specificity tyrosine phosphorylation regulated kinase 3. (584 aa)

Predicted Functional Partners:

tp53

0.720

LOC108436226

0.720

atm

0.697

dcaf7

0.683

DCAF7

0.683

mdm2

0.674

DCAF1

0.645

lin52

0.624

pin1

0.623

rps27a

0.619

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCAF1	dyrk3	ENSPNAP00000026175	ENSPNAP00000004316	DDB1 and CUL4 associated factor 1.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.645
DCAF7	dyrk3	ENSPNAP00000024715	ENSPNAP00000004316	DDB1 and CUL4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.683
LOC108436226	atm	ENSPNAP00000030579	ENSPNAP00000006479	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Non-specific serine/threonine protein kinase.	0.991
LOC108436226	dyrk3	ENSPNAP00000030579	ENSPNAP00000004316	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.720
LOC108436226	mdm2	ENSPNAP00000030579	ENSPNAP00000002973	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.994
LOC108436226	pin1	ENSPNAP00000030579	ENSPNAP00000011259	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Peptidyl-prolyl cis-trans isomerase.	0.864
LOC108436226	rps27a	ENSPNAP00000030579	ENSPNAP00000008071	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ribosomal protein S27a.	0.937
LOC108436226	tp53	ENSPNAP00000030579	ENSPNAP00000014501	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.876
atm	LOC108436226	ENSPNAP00000006479	ENSPNAP00000030579	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.991
atm	dyrk3	ENSPNAP00000006479	ENSPNAP00000004316	Non-specific serine/threonine protein kinase.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.697
atm	mdm2	ENSPNAP00000006479	ENSPNAP00000002973	Non-specific serine/threonine protein kinase.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.939
atm	tp53	ENSPNAP00000006479	ENSPNAP00000014501	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.991
dcaf7	dyrk3	ENSPNAP00000011190	ENSPNAP00000004316	WD_REPEATS_REGION domain-containing protein.	Dual specificity tyrosine phosphorylation regulated kinase 3.	0.683
dyrk3	DCAF1	ENSPNAP00000004316	ENSPNAP00000026175	Dual specificity tyrosine phosphorylation regulated kinase 3.	DDB1 and CUL4 associated factor 1.	0.645
dyrk3	DCAF7	ENSPNAP00000004316	ENSPNAP00000024715	Dual specificity tyrosine phosphorylation regulated kinase 3.	DDB1 and CUL4 associated factor 7.	0.683
dyrk3	LOC108436226	ENSPNAP00000004316	ENSPNAP00000030579	Dual specificity tyrosine phosphorylation regulated kinase 3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.720
dyrk3	atm	ENSPNAP00000004316	ENSPNAP00000006479	Dual specificity tyrosine phosphorylation regulated kinase 3.	Non-specific serine/threonine protein kinase.	0.697
dyrk3	dcaf7	ENSPNAP00000004316	ENSPNAP00000011190	Dual specificity tyrosine phosphorylation regulated kinase 3.	WD_REPEATS_REGION domain-containing protein.	0.683
dyrk3	lin52	ENSPNAP00000004316	ENSPNAP00000015839	Dual specificity tyrosine phosphorylation regulated kinase 3.	Lin-52 DREAM MuvB core complex component.	0.624
dyrk3	mdm2	ENSPNAP00000004316	ENSPNAP00000002973	Dual specificity tyrosine phosphorylation regulated kinase 3.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.674