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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
litafLipopolysaccharide-induced TNF factor. (182 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
    
 0.892
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
     
 0.689
LOC108440238
Cell death-inducing p53 target 1.
  
 
0.620
rpa1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.543
LOC108439182
Si:dkeyp-75b4.8.
  
 
 
0.524
cenpt
Si:ch211-225g23.1.
    
 0.521
lin52
Lin-52 DREAM MuvB core complex component.
    
 0.509
sh3tc2
SH3 domain and tetratricopeptide repeats 2.
      
 0.508
LOC108432805
Si:ch211-157c3.4.
  
 
 
0.502
lin54
Lin-54 DREAM MuvB core complex component.
    
 0.470
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.