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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sipa1l1Signal-induced proliferation-associated 1 like 1. (1655 aa)    
Predicted Functional Partners:
rap1a
Uncharacterized protein.
    
 0.643
rap1b
RAP1B, member of RAS oncogene family.
    
 0.643
LOC108413334
RAP1A, member of RAS oncogene family b.
    
 0.643
afdn
Afadin, adherens junction formation factor a.
    
 0.608
ENSPNAP00000008217
RAP2B, member of RAS oncogene family.
    
 0.529
LOC108424337
RAP2A, member of RAS oncogene family b.
    
 0.529
LOC108444473
RAP2C, member of RAS oncogene family.
    
 0.529
DIRAS2
DIRAS family GTPase 2.
    
 0.511
LOC108437290
DIRAS family, GTP-binding RAS-like 1a.
    
 0.511
LOC108411187
Uncharacterized protein.
    
 0.511
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.