mocs1 protein (Pygocentrus nattereri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

mocs1

Molybdenum cofactor synthesis 1. (405 aa)

Predicted Functional Partners:

LOC108433528

0.993

gphn

0.944

LOC108443923

0.939

LOC108429343

0.906

gucy2c

0.905

urod

0.903

hddc3

0.903

ENDOV

0.903

gch1

0.900

rnf8

0.899

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENDOV	mocs1	ENSPNAP00000036996	ENSPNAP00000005233	Endonuclease V.	Molybdenum cofactor synthesis 1.	0.903
LOC108429343	gch1	ENSPNAP00000024770	ENSPNAP00000007936	GTP cyclohydrolase 2.	GTP cyclohydrolase 1.	0.881
LOC108429343	gucy2c	ENSPNAP00000024770	ENSPNAP00000008018	GTP cyclohydrolase 2.	Guanylate cyclase.	0.823
LOC108429343	hddc3	ENSPNAP00000024770	ENSPNAP00000033552	GTP cyclohydrolase 2.	HD domain containing 3.	0.837
LOC108429343	mocs1	ENSPNAP00000024770	ENSPNAP00000005233	GTP cyclohydrolase 2.	Molybdenum cofactor synthesis 1.	0.906
LOC108429343	rnf8	ENSPNAP00000024770	ENSPNAP00000006057	GTP cyclohydrolase 2.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.823
LOC108433528	LOC108443923	ENSPNAP00000030904	ENSPNAP00000036914	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	Gephyrin a.	0.992
LOC108433528	gphn	ENSPNAP00000030904	ENSPNAP00000005596	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	Gephyrin b.	0.992
LOC108433528	mocs1	ENSPNAP00000030904	ENSPNAP00000005233	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	Molybdenum cofactor synthesis 1.	0.993
LOC108443923	LOC108433528	ENSPNAP00000036914	ENSPNAP00000030904	Gephyrin a.	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	0.992
LOC108443923	gphn	ENSPNAP00000036914	ENSPNAP00000005596	Gephyrin a.	Gephyrin b.	0.827
LOC108443923	mocs1	ENSPNAP00000036914	ENSPNAP00000005233	Gephyrin a.	Molybdenum cofactor synthesis 1.	0.939
gch1	LOC108429343	ENSPNAP00000007936	ENSPNAP00000024770	GTP cyclohydrolase 1.	GTP cyclohydrolase 2.	0.881
gch1	gucy2c	ENSPNAP00000007936	ENSPNAP00000008018	GTP cyclohydrolase 1.	Guanylate cyclase.	0.840
gch1	hddc3	ENSPNAP00000007936	ENSPNAP00000033552	GTP cyclohydrolase 1.	HD domain containing 3.	0.837
gch1	mocs1	ENSPNAP00000007936	ENSPNAP00000005233	GTP cyclohydrolase 1.	Molybdenum cofactor synthesis 1.	0.900
gch1	rnf8	ENSPNAP00000007936	ENSPNAP00000006057	GTP cyclohydrolase 1.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.823
gphn	LOC108433528	ENSPNAP00000005596	ENSPNAP00000030904	Gephyrin b.	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	0.992
gphn	LOC108443923	ENSPNAP00000005596	ENSPNAP00000036914	Gephyrin b.	Gephyrin a.	0.827
gphn	mocs1	ENSPNAP00000005596	ENSPNAP00000005233	Gephyrin b.	Molybdenum cofactor synthesis 1.	0.944