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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
igfbp7Insulin-like growth factor binding protein 7. (277 aa)    
Predicted Functional Partners:
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.673
frem1
Fras1 related extracellular matrix 1a.
      
 0.670
LOC108429520
Fras1 related extracellular matrix 1b.
      
 0.670
LOC108438546
Insulin-like growth factor 2a.
    
 
 0.625
LOC108439146
JunE proto-oncogene, AP-1 transcription factor subunit.
    
  0.574
jun
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
    
  0.574
hus1
Checkpoint protein; Belongs to the HUS1 family.
      
 0.567
LOC108425411
Prokineticin receptor 1b; Belongs to the G-protein coupled receptor 1 family.
      
 0.566
LOC108441199
Prokineticin receptor 1a; Belongs to the G-protein coupled receptor 1 family.
      
 0.566
fam20b
FAM20B glycosaminoglycan xylosylkinase.
   
 
  0.565
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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