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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ1-2Potassium voltage-gated channel subfamily J member 1. (372 aa)    
Predicted Functional Partners:
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.529
ENSPNAP00000002058
Potassium inwardly-rectifying channel, subfamily J, member 1b.
  
  
 
0.463
ENSPNAP00000000745
ABC transporter domain-containing protein.
    
 0.433
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8.
    
 0.433
LOC108439416
ATP-binding cassette, sub-family C (CFTR/MRP), member 9.
 
  
 0.433
LOC108430275
ATP-binding cassette, sub-family C (CFTR/MRP), member 8b.
    
 0.433
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3.
    
 0.413
LOC108430865
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a.
    
 0.413
abcc1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1.
    
 0.413
LOC108437999
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1.
    
 0.413
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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