STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lac1Sphingosine N-acyltransferase lac1. (409 aa)    
Predicted Functional Partners:
Acer3
Alkaline ceramidase 3.
    
 0.938
dsd1
Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
    
 0.934
LCB5
Sphingoid long chain base kinase 5.
     
 0.928
sur2
Sphingolipid C4-hydroxylase sur2; Belongs to the sterol desaturase family.
   
 0.926
YSR3
Dihydrosphingosine 1-phosphate phosphatase YSR3.
    
 0.925
lag1
Sphingosine N-acyltransferase lag1.
     
 
0.900
SCS7
Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily.
   
 
 0.630
TSC10
3-ketodihydrosphingosine reductase.
     
 0.517
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.