STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
impact-AProtein IMPACT-A. (251 aa)    
Predicted Functional Partners:
tmp1b
Thymidylate kinase.
    
  0.690
SER3
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.684
Dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase.
    
  0.663
Gcsh
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
    
  0.594
dld1
Dihydrolipoyl dehydrogenase.
   
 
  0.481
gyaR
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.444
GLR1
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
  0.444
DNF11_3762
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.444
DNF11_2260
LsmAD domain-containing protein.
    
 
 0.435
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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