STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hem14Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (435 aa)    
Predicted Functional Partners:
fech
Ferrochelatase, mitochondrial; Belongs to the ferrochelatase family.
 
 
 0.997
hem12
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
 
 0.996
Coprox
Coproporphyrinogen-III oxidase.
  
 
 0.988
galE
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
  0.725
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 0.700
ups1
Uroporphyrinogen-III synthase.
  
  
 0.674
HEM3
Porphobilinogen deaminase.
  
  
 0.673
hem-1
5-aminolevulinate synthase, mitochondrial.
      
 0.598
etp1
Electron transfer protein 1, mitochondrial.
   
  
 0.553
DNF11_3374
Uncharacterized protein.
  
  
 0.484
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.