STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (331 aa)    
Predicted Functional Partners:
GET1
Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (By similarity).
    
 0.993
MGL_0805
Uncharacterized protein.
    
 0.992
MGL_1698
Uncharacterized protein.
   
 0.948
MGL_3886
TPR_REGION domain-containing protein.
   
 0.815
MGL_3067
Uncharacterized protein.
    
 0.788
MGL_0527
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
   
 0.709
MGL_1516
V-SNARE coiled-coil homology domain-containing protein.
   
 
 0.635
MGL_3664
Ytp1 domain-containing protein.
    
 0.595
MGL_3930
Ubiquitin-like domain-containing protein.
   
 0.570
MGL_1638
Plug_translocon domain-containing protein.
    
 
 0.568
Your Current Organism:
Malassezia globosa
NCBI taxonomy Id: 425265
Other names: M. globosa CBS 7966, Malassezia globosa CBS 7966
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