STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikRNickel responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (143 aa)    
Predicted Functional Partners:
mazF
Potassium ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
KGI53187.1
MazF family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
nadD
Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.832
rsfS
Oligomerization domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.740
exbB
Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.687
KGI54251.1
Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
     0.658
KGI54245.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.652
exbD
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.607
KGI53578.1
Molybdenum-pterin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.602
KGI54307.1
Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.458
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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