STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikRNickel responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (143 aa)    
Predicted Functional Partners:
mazF
Potassium ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.844
KGI53187.1
MazF family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.844
nadD
Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.814
rsfS
Oligomerization domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.741
exbB
Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.696
KGI54251.1
Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
     0.651
KGI54245.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.647
exbD
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.605
hypB
Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.521
rpoB
DNA-directed RNA polymerase subunit beta/beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.445
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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