Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGI54251.1Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (222 aa)    
Predicted Functional Partners:
exbD
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.979
exbB
Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.974
exbB-2
Biopolymer transporter ExbB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.920
KGI54532.1
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.916
KGI54321.1
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.835
KGI54422.1
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.834
KGI54320.1
Flagellar motor protein MotA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.821
KGI54052.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.769
KGI54572.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
  0.714
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.707
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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