STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGI54412.1COP-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)    
Predicted Functional Partners:
KGI54413.1
ATPase P; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.981
KGI54657.1
Metal ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
KGI54411.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.818
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.692
KGI53473.1
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.664
KGI54414.1
Nuclease NucT; Membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.601
KGI53944.1
Potassium transporter KefB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.494
KGI54444.1
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
  
  
 0.470
KGI54630.1
Metal-sensitive transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.465
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.407
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.