Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGI54850.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (236 aa)    
Predicted Functional Partners:
KGI53530.1
Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
 
 
 0.950
KGI54195.1
Octaprenyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family.
 
 
 0.949
KGI54620.1
CDP-diglyceride synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family.
  
  
 0.933
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.918
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.873
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
 
  
 0.856
rpoB
DNA-directed RNA polymerase subunit beta/beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.856
KGI54848.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.818
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.806
nusA
Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
  
    0.793
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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