STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGI54932.13-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (393 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 
 0.981
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsB family.
 
  
 0.979
KGI54829.1
Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.970
waaC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.950
KGI54573.1
ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.939
KGI54933.1
Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.837
KGI54468.1
ipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.831
KGI53799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.811
KGI53222.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.811
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.796
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
Server load: medium (44%) [HD]
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