Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGI54962.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (218 aa)    
Predicted Functional Partners:
KGI54959.1
Hypothetical protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
    
  0.843
KGI54961.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.793
KGI53572.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.791
KGI54960.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.777
KGI54958.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
KGI54963.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.768
KGI54964.1
Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.417
KGI54894.1
2-acyl-glycerophospho-ethanolamine acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.400
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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