STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGI53454.1Hypothetical protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. (160 aa)    
Predicted Functional Partners:
KGI53453.1
Hypothetical protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.
 
    
0.856
KGI53508.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.745
KGI53853.1
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.745
KGI53556.1
Hypothetical protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.
  
     0.740
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
   0.402
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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