Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGI53565.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)    
Predicted Functional Partners:
KGI54726.1
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.864
oadA
Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.855
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.818
KGI54499.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.814
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.795
KGI53615.1
Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.783
KGI54633.1
2-hydroxyacid dehydrogenase; Involved in the metabolism of aromatic amino acids; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.782
serB
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.781
KGI54348.1
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 
 0.775
trpF
Phosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family.
    
  0.767
Your Current Organism:
Helicobacter japonicus
NCBI taxonomy Id: 425400
Other names: ATCC TSD-46, H. japonicus, Helicobacter japonicum, Helicobacter sp. MIT 01-6451, LMG 28612, LMG:28612, strain MIT 01-6451
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